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GOP frontrunner expects "uphill climb" as campaign shifts to South Carolina, but says he has "broad shoulders"

Joran van der Sloot pleaded guilty on Wednesday to the 2010 murder of a 21-year-old Peruvian woman he met at a Lima casino who was killed five years to the day of the unsolved disappearance in Aruba of an American teen in which he remains the main suspect.

Peruvian woman was killed 5 years to the day of unsolved disappearance of Natalee Holloway